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Shaun Zandnia haemophilia a) The main symptom of bleeders disease is expel. Mild cases whitethorn go unnoticed until later in life, when they occur during surgical process or after trauma. In more severe cases, expert haemorrhage may occur without any cause. Internal bleeding may occur anywhere. Bleeding into joints is common. b) (See table below for chart) hemophilia A (clotting component VIII deficiency) is the or so common rebound of the dis guild, occurring at round 1 in 5,00010,000 male births. bleeders disease B (factor IX deficiency) occurs at or so 1 in about 20,00034,000 male births. It is very unlikely for a womanish to be affected c) Current research beas and intercessions under psychoanalysis include: Recombinant factor VIII factortically engineered to avoid risks of disease transmittal by infusion and also gene therapy. d) Direct revolution Testing For Hemophilia A and B, it is possible to reflexion for mutations indoors the gene. Thi s approach is called look at DNA interrogatory and is the most accurate method for identifying common carriers. A blood smack from the male family member with hemophilia is analyse first. In about 98% of cases, a mutation send word be identified. Next, a blood sample from the woman desiring carrier interrogatory is obtained, and her DNA is checked for the specific mutation.

Such interrogation is performed at specialized laboratories. Results are generally available in several(prenominal) weeks.  Linkage (Indirect) Testing In some cases of Hemophilia A and Hemophilia B, a mutation cannot be identified. Ho wever, it may be possible to use indirect or! linkage tests to look on the gene carrier status of females by introduce the gene in the family. Blood samples are obtained from the male with hemophilia and early(a) family members. Patterns of linked DNA in the person with hemophilia are compared to the DNA in family members to check for the same pattern. Linkage exam is not as accurate as direct examen and does not provide information for all families. e) The main word for hemophilia is...If you want to get a full essay, say it on our website: OrderCustomPaper.com

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